foetus through the mother's blood-stream. This in itself was a notable achievement, because the circulatory systems of mother and foetus are fairly well insulated from each other by a filtering membrane. One of Trelone's difficulties was that the hormone caused growth in the maternal as well as the foetal brain, and since the mother's skull was adult and rigid there must inevitably be very serious congestion, which would lead to death unless some means were found to insulate her brain from the stimulating drug. This difficulty was eventually overcome. At last it became possible to assure the unborn animal a healthy maternal environment. After its birth Trelone periodically added doses of the hormone to its food, gradually reducing the dose as the growing brain approached what he considered a safe maximum size. He had also devised a technique for delaying the closing of the sutures between the bones of the skull, so that the skull might continue to expand as required.
A large population of rats and mice was sacrificed in the attempt to perfect Trelone's technique. At last he was able to produce a number of remarkable creatures. His big-headed rats, mice, guinea-pigs, rabbits, though their health was generally bad, and their lives were nearly always cut short by disease of one kind or another, were certainly geniuses of their humble order. They were remarkably quick at finding their way through mazes, and so on. In fact they far excelled their species in all the common tests of animal intelligence, and had the mentality rather of dogs and apes than of rodents.
But this was for Trelone only the beginning. While he was improving his technique so that he could ensure a rather more healthy animal, he at the same time undertook research into methods of altering the tempo of its life so that it should mature very slowly and live much longer than was normal to its kind. Obviously this was very important. A bigger brain needs a longer life-time to fulfil its greater potentiality for amassing and assimilating experience. Not until he had made satisfactory progress in both these enterprises did he begin to experiment on animals of greater size and higher type. This was a much more formidable undertaking, and promised no quick results. After a few years he had produced a number of clever but seedy cats, a bright monkey that died during its protracted adolescence, and a dog with so big a brain that its crushed and useless eyes were pushed forward along its nose. This creature suffered so much that its producer reluctantly destroyed it in infancy.
Not till several more years had elapsed, had Trelone perfected his technique to such an extent that he was able to pay less attention to the physiological and more to the psychological aspect of his problem. Contrary to his original plan, he worked henceforth mainly on dogs rather than apes. Of course apes offered the hope of more spectacular success. They were by nature better equipped than dogs. Their brains were bigger, their sight was more developed, and they had hands. Nevertheless from Trelone's point of view dogs had one overwhelming advantage. They were capable of a much greater freedom of movement in our society. Trelone confessed that he would have preferred to work on cats, because of their more independent mentality; but their small size made them unsuitable. A certain absolute bulk of brain was necessary, no matter what the size of the animal, so as to afford a wealth of associative neural paths. Of course a small animal did not need as large a brain as a large animal of the same mental rank. A large body needed a correspondingly large brain merely to work its machinery. A lion's brain had to be bigger than a cat's. An elephant's brain was even larger than a much more intelligent but smaller man's. On the other hand, each rank of intelligence, no matter what the size of the animal, required a certain degree of complexity of neural organization, and so of brain bulk. In proportion to
Christopher Knight, Alan Butler